解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::It is known that many medical adverse events can be caused by nonsteroidal anti-inflammatory drugs (NSAIDs); however, epidemiologic evidence has not granted an affirmative relationship between NSAID use and the risk of end-stage renal disease (ESRD). We aimed to investigate the relationship in a Chinese population bet...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001362
更新日期:2015-09-01 00:00:00
abstract::The positive results of recent trials for the treatment of acute ischemic stroke have highlighted the importance of imaging selection before endovascular therapy. We performed a stratified meta-analysis to confirm this new understanding. We searched EMBASE, PubMed, Cochrane Central Register of Controlled Trials, and C...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000001539
更新日期:2015-09-01 00:00:00
abstract::The association between the hepatitis C virus (HCV) infection and the risk of myocardial infarction (MI) and stroke has been previously investigated. However, the association between the HCV infection and the risk of venous thromboembolism (VTE) has not been extensively discussed. Using the Longitudinal Health Insuran...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001585
更新日期:2015-09-01 00:00:00
abstract::To compare the clinical outcome of digital and manual marking for toric intraocular lens (IOL) alignment. This is a prospective clinical study that included 60 eyes of 60 patients undergoing cataract surgery with coexisting corneal astigmatism more than 1 diopter (D). The eyes were randomly assigned to either digital ...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000001618
更新日期:2015-09-01 00:00:00
abstract::In this study, a constant pressure stimulus was applied on the 3 joints (first [p1], second [p2], and third [p3] joints) of 4 fingers (index, middle, ring, and little fingers), and the activation areas within Brodmann area 2 (BA 2) were compared for these different fingers and joints by using functional magnetic reson...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001657
更新日期:2015-09-01 00:00:00
abstract::High occupational stress and burnout among physicians can lead to sleep problems, anxiety, depression, and even suicide. Even so, the actual risk for these behavioral health problems in health care-seeking physicians has been seldom explored. The aim of this study was to determine whether physicians have higher odds o...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001323
更新日期:2015-09-01 00:00:00
abstract::Although step counters are increasingly being used in walking programmes to promote sedentary behavior changes in adults, their effectiveness remains unknown. The aim of this meta-analysis of randomized controlled trials (RCTs) was to assess the effectiveness of step counter use in reducing sedentary time among adults...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001412
更新日期:2015-09-01 00:00:00
abstract::The study aim is to compare anal intraepithelial neoplasia (AIN) progression and regression rates in a cytology inception cohort to estimates based on the subcohort referred for ≥1 high-resolution anoscopies (HRAs).A cytology-based retrospective cohort was assembled including the anal cytology histories and invasive a...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001476
更新日期:2015-09-01 00:00:00
abstract::Recent advances in breast cancer management might make the use of postmastectomy radiotherapy (PMRT) redundant in the treatment of pT1/T2N1 patients. We investigated the impact of PMRT on disease-free survival (DFS) in these patients who have a low risk of locoregional recurrence (LRR) after contemporary multidiscipli...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001259
更新日期:2015-08-01 00:00:00
abstract::Serum adiponectin levels have been suggested to be predictors of type 2 diabetes mellitus in diverse populations. However, the relationship between circulating adiponectin levels and the risk of development of type 2 diabetes in postmenopausal women has not been investigated.A total of 382 healthy postmenopausal women...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001347
更新日期:2015-08-01 00:00:00
abstract::This study investigated anatomical variations in the confluence types of the right gastroepiploic vein (RGEV) to improve knowledge regarding no. 6 lymphadenectomy for laparoscopic gastrectomy.The RGEV drainage patterns of 144 patients who were diagnosed with gastric cancer and underwent laparoscopic distal gastrectomy...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001383
更新日期:2015-08-01 00:00:00
abstract::Immune thrombocytopenic purpura (ITP) is a life-threatening complication following pegylated interferon alpha (PEG-IFN) plus ribavirin treatment, the standard treatment for hepatitis C virus (HCV) infection. We reported a rare case with late-onset ITP after withdrawal of PEG-IFN treatment.A 53-year-old male with hepat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001296
更新日期:2015-08-01 00:00:00
abstract::Hypertension should be best managed under primary care settings. This study aimed to compare, between Shanghai and Shenzhen, the perceived quality of primary care in terms of accessibility, continuity, co-ordination, and comprehensiveness among hypertensive patients.A cross-sectional study was conducted in Shanghai an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001388
更新日期:2015-08-01 00:00:00
abstract::New York City is a multicultural city where people of different ethnicities and backgrounds from all over the world live together. Of the different ethnicities, it is home to a large population of Western African immigrants. This case report is that of an elderly female of Western African descent presenting to Lincoln...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001415
更新日期:2015-08-01 00:00:00
abstract::Periodontal disease (PD) is prevalent and correlated with malnutrition and inflammation in patients on hemodialysis (HD). Periodontal therapy improves systemic inflammatory and nutritional markers in HD population. The relationship between intensive PD therapy and clinical infectious outcomes in patients on HD remains...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001436
更新日期:2015-08-01 00:00:00
abstract::This study aimed to explore the sensitivity and specificity an approach to confirm the depth of the endotracheal tube. It was a prospective, diagnostic study (Registration number: chiCTR-TRC-14005170) conducted in the Department of Anesthesiology of West China Hospital. A total of 100 patients underwent general anesth...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001460
更新日期:2015-08-01 00:00:00
abstract::This article evaluates the long-term outcomes of computed tomography (CT)-guided percutaneous radiofrequency thermocoagulation (PRT) for patients with recurrent trigeminal neuralgia (TN) after microvascular decompression (MVD).This is a retrospective study of 41 patients with intractable TN who after MVD underwent CT-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001176
更新日期:2015-08-01 00:00:00
abstract::Abnormalities in the levels of calcium, phosphorus, and parathyroid hormone (PTH) in serum are typical for patients with chronic kidney disease (CKD). They are used routinely to predict the onset of CKD-mineral and bone disorder (MBD). However, CKD-MBD associated with metabolic pathway imbalance is not well understood...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001273
更新日期:2015-08-01 00:00:00
abstract::Recently, much attention has been paid to a potential biochemical cross-talk between the metabolism of the adipose tissue (AT) and bone (marrow), termed "bone-fat axis." We hypothesized that selected substances, participating in this "dialog," are associated with body mass and peripheral trafficking of bone marrow-der...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001303
更新日期:2015-08-01 00:00:00
abstract::Emerging evidences showed impaired muscle strength was prevalent in older adults with mild cognition impairment or dementia. However, little was known about the role of quadriceps strength in the cognition decline among older population. The objective of our study was to investigate the relation between quadriceps str...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001335
更新日期:2015-08-01 00:00:00
abstract::One strategy for controlling the skyrocketing costs of cancer care may be to target high-tech/high-cost imaging at the end of life (EOL). This population-based study investigated receipt of high-tech/high-cost imaging and its determinants for Taiwanese patients with metastatic cancer in their last month of life.Indivi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001354
更新日期:2015-08-01 00:00:00
abstract::Several epidemiological studies have focused on the role of nuclear factor-kappa-B inhibitor-alpha (NFKBIA) -881 A>G polymorphism in cancer susceptibility. However, the published data have led to contentious results. This study was designed to examine the association between -881 A>G polymorphism and cancer risk.Compr...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001024
更新日期:2015-08-01 00:00:00
abstract::This study investigated the prevalence of smoking, alcohol consumption, and physical activity in cancer survivors and examined the sociodemographic factors affecting these health-related behaviors.We used data from the 4th and 5th Korean National Health and Nutrition Examination Survey conducted between 2007 and 2012,...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001214
更新日期:2015-08-01 00:00:00
abstract::Isoflurane is a volatile halogenated anesthetic used especially for anesthesia maintenance whereas propofol is a venous anesthetic utilized for anesthesia induction and maintenance, and reportedly an antioxidant. However, there are still controversies related to isoflurane-induced oxidative stress and it remains unans...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000001266
更新日期:2015-08-01 00:00:00
abstract::We evaluated the tumor response and survival according to the KRAS oncogene status in locally advanced rectal cancer. One hundred patients with locally advanced rectal cancer (cT3-4N0-2M0) received preoperative radiation of 50.4 Gy in 28 fractions with 5-fluorouracil and total mesorectal excision. Tumor DNA from each ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001284
更新日期:2015-08-01 00:00:00
abstract::The role of cancer stem cell (CSC) markers in differentiation of hepatocellular carcinoma (HCC) remains uncertain. We conducted a meta-analysis to first investigate the association between expression of CSC markers (CD133, CD90, CD44, and EpCAM) and poor differentiation of HCC, and second, to determine if these CSC ma...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000001306
更新日期:2015-08-01 00:00:00
abstract::The contributions of micro RNAs (miRNAs) to rheumatoid arthritis (RA) are beginning to be uncovered during the last decade. Many studies in efforts to use miRNAs as biomarkers in disease diagnosis, prognosis, and treatment are ongoing.We conducted a systematic literature review to reveal the role of miRNAs in the path...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000001326
更新日期:2015-08-01 00:00:00
abstract::The porphyrias are a group of rare metabolic disorders. The incidence and prevalence are low because the acute intermittent porphyria (AIP) is rare. Our aim was to assess the use of anthropometric and quality-of-life parameters in porphyric patients in order to identify predictor factors that might help in characteriz...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001023
更新日期:2015-07-01 00:00:00
abstract::To evaluate the value of lymph node status of primary tumors in predicting the prognosis of synchronous resectable metastatic colorectal cancer (mCRC).The characteristics of resectable mCRC are substantially different from other cancers, and the prognostic factors of resectable mCRC are still controversial.The data of...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001215
更新日期:2015-07-01 00:00:00
abstract::To assess prognostic factors for survival and describe Model for End-Stage liver disease (MELD) dynamics in human immunodeficiency virus+/hepatitis C virus+ (HIV+/HCV+) patients after an initial episode of hepatic decompensation.An HIV+/HCV+ cohort of patients experiencing an initial decompensation episode within the ...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000001239
更新日期:2015-07-01 00:00:00
abstract::Systemic activation of hemostasis and thrombosis has been implicated in tumor progression and metastasis. D-dimer has been used as an indicator for the thrombosis. Here, we investigated the role of the activation of coagulation in patients with metastatic gastric cancer by measuring D-dimer level.We conducted an obser...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000951
更新日期:2015-07-01 00:00:00
abstract::The purpose of this study was to perform a meta-analysis on the efficacy of ibandronate by evaluating the effect sizes of different dosing regimens.Major electronic databases were searched from 1985 to February 2015. A random effects meta-analysis was performed in STATA.Data from 34 studies (13,639 patients) were incl...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001007
更新日期:2015-07-01 00:00:00
abstract::Within the overall National Health Insurance (NHI) budget in Taiwan, there has been a remarkable increase in expenditure for cancer patients. This study was designed to explore whether hematological malignancy is associated with higher end-of-life (EOL) medical expenditure in their last 6 months of life.We used data f...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001036
更新日期:2015-07-01 00:00:00
abstract::Cirrhosis and idiopathic portal hypertension (IPH) are 2 major diseases showing portal hypertension. However, characteristics and outcomes of IPH with ascites have not yet been determined. The aim of the study was to examine the influence of ascites on the long-term clinical course of IPH.This observational study comp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001056
更新日期:2015-07-01 00:00:00
abstract::Informed consent has now become common in medical practice. However, a gap still exists between doctors and patients in the understanding of clinical conditions. We designed medical comics about "subarachnoid hemorrhage" and "intracerebral hemorrhage" to help doctors obtain informed consent intuitively, quickly, and c...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001077
更新日期:2015-07-01 00:00:00
abstract::Irreversible electroporation (IRE) is a new nonthermal tumor ablation modality that induces apoptosis in the treated tissue without affecting collagen. Its use is particularly indicated for tumors involving major structures, such as encompassed or infiltrated vessels and/or ducts, which need to be preserved and hinder...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000946
更新日期:2015-07-01 00:00:00
abstract::Several studies have reported the relationship between alcoholic liver disease (ALD) and carotid intima-media thickness (CIMT). Few studies, however, have investigated the causes of CIMT thickening in patients with ALD. The authors explored the causes of CIMT thickening in patients with ALD. The authors enrolled 152 p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001087
更新日期:2015-07-01 00:00:00
abstract::A minimum of 12 harvested lymph nodes (hLNs) are recommended in colorectal cancer. However, a paucity of hLNs is frequently presented after preoperative chemoradiation (pCRT) in rectal cancer and the significance of this is still uncertain. The aim of this study is to analyze the impact of hLNs on long-term oncologic ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001133
更新日期:2015-07-01 00:00:00
abstract::To investigate the effect of different dialysis modalities on the incidence of peripheral artery occlusive disease (PAOD) among patients with end-stage renal disease (ESRD) in a large population-based cohort study. The cohort study included 26,927 ESRD patients who underwent hemodialysis (17,737 patients, hemodialysis...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001164
更新日期:2015-07-01 00:00:00
abstract::Primary squamous cell carcinoma (SCC) of liver is rare, and its prognosis is extremely poor. This study aims at reviewing the clinical data of all pathologically diagnosed liver cancer in our institute, and discussing the clinical presentation, diagnosis, treatment, and prognosis of our cases of SCC and the literature...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000000868
更新日期:2015-07-01 00:00:00